For Practices
Clinical Research Infrastructure for Specialist Practices
Vellum SMO helps qualified specialist physician practices launch research capability without disrupting core clinical operations. We bring sponsor-funded opportunities, regulatory structure, and operational support so your team can participate with confidence.
Our Model
A Structured Path Into Research
We work alongside specialist practices to establish the infrastructure required for clinical research participation. Our model is designed to align research activity with existing standards of care, physician workflows, and long-term practice goals.
Sponsor-funded activation
We identify appropriate trial opportunities and connect practices to sponsor and CRO demand through the Vellum network.
Operational support
We manage key regulatory, administrative, and site-readiness functions so practices can enter research with a disciplined operating model.
What Practices Gain
Built for Specialist Sites
Vellum SMO is designed for practices that want to add research capability in a measured, professional way. We help create the conditions for participation while preserving focus on patient care and physician leadership.
Site activation
Assessment, onboarding, and implementation support to prepare the practice for research participation.
Regulatory framework
Structured processes and documentation support to help practices meet sponsor and study expectations.
Operational integration
Workflow planning that fits research activity alongside existing clinic operations and staff responsibilities.
Revenue diversification
Access to sponsor-funded trial opportunities that can create an additional line of business for qualified practices.
What Partnership Looks Like
From initial evaluation through launch readiness, Vellum provides the infrastructure and coordination needed to help practices participate in clinical research with institutional rigor.
We focus on specialist environments where quality, physician alignment, and operational discipline matter. The result is a practical pathway into research participation for practices that want to grow thoughtfully.
For Practices
Research capability built around your practice
Vellum SMO establishes the operational, regulatory, and commercial infrastructure your practice needs to participate in sponsor-funded clinical research — without changing how you run your clinical business.
Our Model
What partnership with Vellum looks like
A structured partnership designed to add research capability without disrupting clinical operations.
We build the infrastructure
Vellum manages site activation, regulatory documentation, study coordination, and sponsor contracting. Your practice focuses on clinical care and research execution — not administrative overhead.
You place qualified investigators
Participating physicians serve as Principal Investigators on studies placed at your site. That work is compensated directly — separate from, and in addition to, your clinical revenue.
We share in the outcome
Vellum practices participate in network-level research revenue on a quarterly basis, and in value created at the network level over time. This is a partnership structure, not a vendor relationship.
For Practices
Three ways your practice benefits
Vellum creates immediate and long-term economic participation for qualified specialist practices.
Direct investigator compensation
Physicians and licensed clinical staff earn professional fees on every study placed at your site — paid by sponsors through Vellum as sponsor pass-through compensation.
Quarterly network distributions
Participating practices receive a share of Vellum SMO’s net research revenue each quarter, weighted by your site’s research activity.
Long-term value participation
Practices share in the long-term value of the Vellum network. As the platform grows and matures, founding practices participate in that outcome.
We carry the operational weight
Vellum manages the infrastructure that most practices don’t have in-house: site feasibility and activation, IRB coordination, regulatory documentation, sponsor contracting, study placement, and ongoing compliance oversight. Our goal is to make research participation as operationally clean as possible so it complements — rather than competes with — your existing clinical practice.
Find out if your practice is a fit
Vellum works with specialist practices across the United States in a limited number of therapeutic areas. We’re selective about the practices we partner with and the studies we place. If you’re interested in exploring research participation, get in touch.